A sample of patients affected with chronic respiratory tract infection
DOI:
https://doi.org/10.15218/zjms.2012.0021Keywords:
Cryptococcosis, Chronic respiratory disease, immunocompromisedAbstract
Background and objectives: Cryptococcosis is subacute or chronic respiratory disease caused by yeast like fungus called Cryptococcus neoformans. The disease may metastasize to CNS and other parts of the body. The objective of the study is to find the prevalence of this disease in a sample of patients in Erbil.
Method: One hundred and twenty eight patients with chronic respiratory tract infection were included in this study. Early morning sputum sample was collected from each patient and subjected to both direct examination and culture
Results: The study showed 24 positive cases of Cryptococcosis, from the total 128 patients examined; 16 of them (66.6%) gave positive culture for Cryptococcus neoformans while 8 (33.3%) gave positive culture for opportunistic species of Cryptococcus. The latter were immunocompromised individuals.
Conclusion: It is concluded that looking for Cryptococcus, is quite significant in patients with chronic respiratory diseases.
Metrics
References
Conant N F, Smith T D, Baker R D, Callaway J L, Martin D S. Manual of clinical mycology, Philadelphia and London. Saunders. 1971; 149
Dabbagh R., Conant N F, Nielsen H S, Burns RO. Effect of temperature on cryptococcosis. J. General Micro. 1974; 85: I77-202.
Boekhout T, Theelen B, Diaz M, Fell W, Jack C, Wim A C, Dromer F, et al. Hybrid genotypes in the pathogenic yeast Cryptococcosis neoformans. Society for General Microbiology 2001;147: 891-901.
Kakeya H, Udono H, Maesaki S, Sasaki E , Kawmura S, Hossain M, et al . Heat shock protein 70(hsp70) as major target of the antibody response in patients with pulmonary cryptococcosis. Clin Exp Immunology 1999;115(3): 485-490.
Faress M D, Hejal K. Anal pulmonary cryptococcosis due to Cryptococcus albidus in patient on Infliximab. Disease 2004; 2: 30-33.
Kordossis T, Avlami A , Velegraki I , Georgakopoulos G, Papalambrou C, Legakis N J, First report of Cryptococcus laurenttii meningitis and fetal case of Cryptococcus albidus in AIDS patients. Med. Mycology 1998; 36:335-339.
Ikeda R, Sugita H, Takshi Erie S, Shinoda H , Takako. Laccase and Melanization in Clinical Important Cryptococcus Species Other than Cryptococcus neoformans. Clinical Microbiology 2002; 40: 1214-1218.
Duperval R, Hermans P R , Brewer N S, Roberts G D. Cryptococcosis with emphasis on the significance of isolation of Cryptococcus neoformons from the respiratory tract .Chest 1997;72: 13-19.
Fernando L, Cabral P W. Animals and human beings as reservoirs for human Cryptococcus neoformans infection. Rev. Iberoam Micol. 1999;16:77-81.
Davi L , Goldman J D, Frank B X, Arturo C. Enhanced Allergic Inflammation with Chronic Cryptococcus neoformans infection: Oxford Journals Medicine Journal of Infectious diseases 2006; 193,(8): 1178-1186.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2012 Khonaw kader salih, Rassool A. Dabbagh, Abdulaziz Y. Mansoor (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The copyright on any article published in Zanco J Med Sci is retained by the author(s) in agreement with the Creative Commons Attribution Non-Commercial ShareAlike License (CC BY-NC-SA 4.0).