TY - JOUR AU - Ibrahim, Abdullah Saeed PY - 2021/12/23 Y2 - 2024/03/28 TI - A Relationship between blood group and gastric carcinoma in Erbil city: A case-control study JF - Zanco Journal of Medical Sciences (Zanco J Med Sci) JA - Zanco J Med Sci VL - 25 IS - 3 SE - Original Articles DO - 10.15218/zjms.2021.029 UR - https://zjms.hmu.edu.krd/index.php/zjms/article/view/707 SP - 633-637 AB - <p><strong>Background and objective:</strong> Gastric carcinoma can be caused by the interaction between environmental factors and genetic variations. The relationship between ABO blood groups and carcinogenesis or progression of human tumors has been reported by many investigations. This study aimed to understand the correlation between ABO blood groups and the risk of developing gastric carcinoma.</p><p><strong>Methods:</strong> This case-control study included the ABO blood group and rhesus system of 92 patients diagnosed with gastric carcinoma at Erbil city from 2017 to 2019. Informed consent was obtained from all patients. As a control, the blood group from 260 healthy blood donors was collected from Erbil blood bank.</p><p><strong>Results:</strong> Of 92 patients, 58.7% were males, and 41.3% were females. The mean age was 62 (28 - 97) years. Regarding the type of gastric carcinoma, 58.7% were intestinal, and 41.3% were diffuse type. Blood group and rhesus system of patients and control were compared. Blood group O was 47.8% in cases versus 40.8% in control and 42.6% in all participants, followed by blood group A (31.5% of gastric carcinoma patients and 26.5% of control with a total of 27.8% of all participants). Regarding the Rhesus system, 92.4% of cases were Rh<sup>+</sup>, and 7.6% were Rh<sup>-</sup> compared with 92.9% Rh<sup>+</sup>and 7.1% Rh<sup>-</sup> in control. None of them was statistically significant.</p><p><strong>Conclusion: </strong>There was no statistically significant association between blood groups and gastric carcinoma, although blood group O was more common, followed by A.</p> ER -