TY - JOUR AU - Garabet, Sinan Butrus PY - 2013/08/01 Y2 - 2024/03/29 TI - Association of pre-eclampsia with dyslipideamia JF - Zanco Journal of Medical Sciences (Zanco J Med Sci) JA - Zanco J Med Sci VL - 17 IS - 2 SE - Original Articles DO - 10.15218/zjms.2013.0021 UR - https://zjms.hmu.edu.krd/index.php/zjms/article/view/316 SP - 388-392 AB - <p style="text-align: justify; text-justify: inter-ideograph;"><strong style="font-size: 12pt;"><span style="font-family: Arial;">Background and objective:</span></strong> <span style="font-family: Arial; font-size: 12pt;">Pre-eclampsia and eclampsia are claimed to be associated with disturbances in lipid profile. The purpose of this study was to determine any significant association between pre-eclampsia/eclampsia with lipid profile disturbances.</span></p><div><strong><span style="font-family: Arial; font-size: 12pt;">Methods: </span></strong><span style="font-family: Arial; font-size: 12pt;">This prospective study evaluated lipid profile in the second half of pregnancy in 38 pre-eclamptic, 21 ecalmptic woman and compared to 41 age matched healthy pregnant women served as a control for the period of February 2010</span> <span style="font-family: Arial; font-size: 12pt;">– January 2011.</span></div><div><span style="font-family: Arial; font-size: 12pt;"><strong>Results:</strong></span> <span style="font-family: Arial; font-size: 12pt;">Pre-eclamptic women showed a significant increase in the mean serum cholesterol concentration (243.9 mg/dL) during the second trimester when compared with the healthy pregnant controls (212.9 mg/dL), eclamptic women had even a significant higher cholesterol level at a mean of (288.1 mg/dL). Triglyceride level significantly increased in pre-eclamptic (281.7 mg/dL) and eclamptic women (307.4 mg/dL) compared to healthy pregnant control (207.5 mg/dL). LDL level also showed significant increase in pre-eclamtic {143.7 mg/dL} and eclamptic cases (156.5 mg/dL). HDL level though was decreased in pre-eclamptic {41.5 mg/dL} and eclamptic (40.8 mg/dL) but these changes were not significant. </span></div><p style="text-align: justify; text-justify: inter-ideograph;"><strong><span style="font-family: Arial; font-size: 12pt;">Conclusion: </span></strong><span style="font-family: Arial; font-size: 12pt;">Pre-eclampsia and eclampsia are associated with dyslipidemia. This association may be significant in understanding the pathologic processes of preeclampsia and may help in developing strategies for prevention or early diagnosis of the disorder</span><span style="font-family: Arial; font-size: 12pt;">. </span></p> ER -