The correlation between Blood group type and Diabetes Mellitus Type II

Sawer Sabri Mizouri
Department of Medical Laboratory Technology, Shekhan Technical College of Health, Duhok Polytechnic University, Duhok, Kurdistan, Iraq
Share:

Abstract

Background and objective: Type 2 diabetes mellitus is typically a multifactorial disorder involving genetic and environmental factors to variable extents. The aim of this research was to find out if there is a relationship between the “ABO” and “Rhesus” blood groups and type 2 diabetes mellitus.

Methods: A case-control study was carried out at Azadi Teaching Hospital in Duhok city for six months, from 1st July 2019 to 1st January 2020. The study included 800 individuals including 400 randomly selected diabetic patients and 400 non-diabetic adults of both genders. Standard slide agglutination method at room temperature was performed to determine the ABO and Rh blood groups.

Results: Out of 400 patients, 185(46.25%) were male and 215(53.75%) were female. It was found that out of 400 randomly selected patients, majority had O blood group 193(48.25%), 109(27.25%) had A, 65(16.25%) had B, 33(8.25%) had AB group. A higher frequency of O blood group was encountered among the diabetics comparing to the control (48.25% vs. 37.75%). On applying the Chi-square test, the blood groups O and type 2 diabetes mellitus were found to have a statistically significant relationship (Chi-square value - 8.14, P <0.005) and no statistically significant association between the Rh group and type 2 DM was observed (P >0.05).

Conclusion: According to this study, people with the O blood group are at a greater risk of having type 2 diabetes mellitus, but there was no discrepancy in type 2 diabetes mellitus risk between Rhesus positive and negative classes. The level of blood groups A among diabetic patients is also concluded to be substantially lower.

Metrics

Metrics Loading ...

References

  1. Sharjeel S, Wasi M, Jafri A, Raza FA, Tariq Z, Shamim K, et al. The Correlation Between Blood Group Type and Diabetes Mellitus Type II: A Case-Control Observational Study From Pakistan. Cureus. 2021; 13(11):e19898. DOI: 10.7759/cureus.19898. PMID:34976508; PMCID: PMC8712191.
  2. Cho NH, Kirigia J, Mbanya JC, Ogurstova K, Guariguata L, Rathmann W, et al. Diabetes by region, in IDF Diabetes Atlas, 8th ed. IDF. 2017; 66–81. https://www.idf.org/aboutdiabetes/type-2-diabetes.html
  3. Mansour AA, Al Douri F, Diabetes in Iraq: Facing the Epidemic. A systematic Review. Wulfenia. 2015; 22:258–73. https://www.researchgate.net/publication/280084146.
  4. Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al. Pathophysiology of Type 2 Diabetes Mellitus. Int J Mol Sci. 2020; 21(17):6275. DOI:10.3390/ijms21176275.
  5. Wang Z, Liu L, Ji J, Zhang J, Yan M, Zhang J, et al. ABO blood group system and gastric cancer: a case-control study and meta-analysis. Int J Mol Sci. 2012; 13(10):13308–21. https://doi.org/10.3390/ijms131013308
  6. Alkebsi L, Ideno Y, Lee J S, Suzuki S, Nakajima-Shimada J, Ohnishi H, et al. Gastroduodenal Ulcers and ABO Blood Group: the Japan Nurses’ Health Study (JNHS). J Epidemiol. 2018; 28(1):34–40. https://doi.org/10.2188/jea.JE20160204
  7. Vivek S, Jain J, Simon SP, Battur H, Supreetha S, Haridas R. Association of ABO Blood Group and Rh factor with Periodontal Disease in a Population of Virajpet, Karnataka: A Cross-Sectional Study. J Int Oral Health 2013; 5(4):30–4. PMID: 24155617; PMCID: PMC3780381
  8. Meo SA, Suraya F, Jamil B, Ansari MJ, Meo AS, Sattar K, et al. Association of ABO and Rh blood groups with breast cancer. Saudi J Biol Sci. 2017; 24(7):1609–13. https://doi.org/10.1016/j.sjbs.2017.01.058
  9. EISSA AA. ABO and Rh blood groups polymorphism among the Kurds of Duhok, Iraq. Duhok Med J. 2014; 8(1):1–8.
  10. Karagoz H, Erden A, Ozer O, Esmeray K, Cetinkaya A, Avci D, et al. The role of blood groups in the development of diabetes mellitus after gestational diabetes mellitus. Ther Clin Risk Manag. 2015; 11:1613–7. https://doi.org/10.2147/TCRM.S92294
  11. Aggarwal T, Singh D, Sharma B, Siddiqui SS. and Agarwal S. Association of ABO and Rh blood groups with type 2 diabetes mellitus in Muzaffarnagar city. Natl J Physiol Pharm Pharmacol. 2018; 8(2):167–70. DOI:10.5455/njppp.2018.8.0830324082017
  12. Kamil M, Al-Jamal HA, Yusoff NM. Association of ABO blood groups with diabetes mellitus. Libyan J Med. 2010; 5(1):1–4. https://doi.org/10.3402/ljm.v5i0.4847
  13. Fagherazzi G, Gusto G, Clavel-Chapelon F, Balkau B, Bonnet F. ABO and Rhesus blood groups and risk of type 2 diabetes: evidence from the large E3N cohort study. Diabetologia 2015; 58(3):519–22. https://doi.org/10.1007/s00125-014-3472-9
  14. Bener A, Yousafzai MT, The distribution of the ABO blood groups among the diabetes mellitus patients. Niger J Clin Pract. 2014; 17(5):565–8. https://doi.org/10.4103/1119-3077.141418
  15. Waseem AG, Iqbal M, Khan OA, Tahir M. Association of diabetes mellitus with ABO and Rh blood groups. Ann Pak Inst Med Sci. 2012; 8(2):134–6.
  16. Kumar BA, Kaushik DM, Study of relationship between ABO & Rh Blood group and Type 2 Diabetic Mellitus. Int J Med Res Rev. 2016; 4(11):65–9. https://doi.org/10.17511/ijmrr.2016.i11.10
  17. Dali SM, Aour MA, Belmokhtar F, Belmokhtar R, Boazza F. The relationship between ABO/rhesus blood groups and type 2 diabetes mellitus in Maghnia, Western Algeria. South African Family Practice. 2011; 53(6):68–72. https://doi.org/10.1080/20786204.2011.10874154
How to Cite
Sabri Mizouri, S. . (2023). The correlation between Blood group type and Diabetes Mellitus Type II . Zanco Journal of Medical Sciences (Zanco J Med Sci), 27(1), 16–20. https://doi.org/10.15218/zjms.2023.003

Send mail to Author


Send Cancel