Utility of inflammatory makers, alanine aminotransferase, aspartate aminotransferase, and procalcitonin tests in COVID-19

Authors

  • Shkar Rzgar K.Rostam Department of Biology, College of Science, University of Sulaimani, Iraq.
  • Khattab Ahmed Mustafa Shekhany Department of Biology, College of Science, University of Sulaimani, Iraq.
  • Hardi Rafat Baqi Baqi Department of Medical Laboratory Technology, Shaqlawa Technical College, Erbil Polytechnic University, Erbil, Iraq.

DOI:

https://doi.org/10.15218/zjms.2022.003

Keywords:

COVID-19, SARS-CoV-2, Ferritin, Procalcitonin, Alanine aminotransferase, Aspartate aminotransferase

Abstract

Background and objective: Many tests are conducted for monitoring the progression and the severity of coronavirus disease (COVID-19) infection. However, the extent to which these tests are helpful in clinical practice and therapeutics of COVID-19 is still ambiguous. This study aimed to evaluate the feasibility of performing inflammatory marker tests, liver function tests, and procalcitonin test in the diagnosis and monitoring of COVID-19 infection.

Methods: The current study compares the results of alanine aminotransferase, aspartate aminotransferase, ferritin, and procalcitonin tests in two different populations of 123 COVID-19 suspects and a control group of 110 healthy individuals in Erbil city of Kurdistan region of Iraq to search for possible significant differences in both groups.

Results: The COVID-19 group had significantly higher ferritin and procalcitonin mean values than the control group (P = 0.001). The differences between alanine aminotransferase and aspartate aminotransferase were significant in some age and gender classes of both groups. However, the overall differences were not statistically significant (P = 0.339 and 0.286, respectively).

Conclusion: The outcome of the current study suggests that among the group of tests conducted for the study population, the most useful tests are ferritin and procalcitonin to monitor the COVID-19 patients' health status.

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Published

2022-04-25

How to Cite

K.Rostam, S. R., Shekhany, K. A. M. ., & Baqi, H. R. B. (2022). Utility of inflammatory makers, alanine aminotransferase, aspartate aminotransferase, and procalcitonin tests in COVID-19. Zanco Journal of Medical Sciences (Zanco J Med Sci), 26(1), 22–28. https://doi.org/10.15218/zjms.2022.003

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Original Articles