Evaluation of thyroid function in a sample of newborns through different modes of delivery

  • Sasan L. Hanna Department of Pediatrics, College of Medicine, Hawler Medical University, Erbil, Iraq
  • Awat I. Hamadamen Department of Obstetrics and Gynecology, College of Medicine, Hawler Medical University, Erbil, Iraq
  • Dlair A.K. Chalabi Department of Pediatrics, College of Medicine, Hawler Medical University, Erbil, Iraq
Keywords: Congenital hypothyroidism, Hormone, Thyroid-stimulating hormone, Newborn

Abstract

Background and objective: Congenital hypothyroidism is the most common preventable cause of mental retardation detected during early childhood. Its early diagnosis is crucial for a better outcome. Many factors are contributed to this problem including maternal, fetal and others. This study aimed to assess thyroid hormone status in relation to certain obstetrical especially mode of delivery and neonatal factors

Methods: A descriptive cross-sectional study conducted in postnatal care and delivery room (operative and vaginal) of Maternity teaching hospital in Erbil city. Ninety-two babies were included and subdivided into three groups according to their route of delivery. A thyroid stimulating hormone cut off value of 10 was selected as the upper normal level for the purpose of the study.

Results: A significant proportion of babies with cord thyroid stimulating hormone concentration more than 10 mIU/L (25 out of 92) were noticed, and this is near to many previous studies used the same cut off value. Mean of This hormone is relatively increased among newborns of the elective cesarean section while maternal total triiodothyronine and total thyroxine were higher within the elective group. Prenatal evidence of placental calcification and first born babies were associated with higher thyroid stimulating hormone levels.

Conclusion: Emergency cesarean section is less likely to be associated with elevated cord blood thyroid stimulating hormone level compared to other routes of delivery/but this is not confirmatory and recall test is recommended to exclude hypothyroidism.

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Published
2019-04-23
How to Cite
Hanna, S., Hamadamen, A., & Chalabi, D. (2019). Evaluation of thyroid function in a sample of newborns through different modes of delivery. Zanco Journal of Medical Sciences (Zanco J Med Sci), 23(1), 113-121. https://doi.org/10.15218/zjms.2019.015
Section
Original Articles