Ultrasonographic prevalence of polycystic ovarian morphology among women of reproductive age group

  • Aska Farouq Jamal Department of Surgery, College of Medicine, Hawler Medical University, Erbil, Iraq
  • Media Ghazi Sedeq Department of Surgery, College of Medicine, Hawler Medical University, Erbil, Iraq
  • Ronak Ali Ismael Directorate of Health, Erbil, Iraq
Keywords: Polycystic ovary, Ultrasound, Infertility, Rizgary Teaching Hospital

Abstract

Background and objective: Polycystic ovarian cyst is the most common and complex reproductive endocrinopathy affecting females of childbearing age. This study aimed to investigate the sonographic prevalence of polycystic ovary morphology among women of reproductive age group, and correlate it with age, menstrual disturbances, fertility problems, obesity, and hormonal profile.

Methods: This study was carried out in the Rizgary Teaching Hospital and private clinic in Erbil city, Kurdistan region of Iraqfrom 1st August 2016 to 1st June 2017. A total of 782 women were included in this study. Inclusion criteria were any woman attending to pelvic ultrasound for whatever the cause other than pregnancy. The prevalence of polycystic ovary morphology was determined depending on Rotterdam's criteria; correlation with clinical history and biochemical indices was done.

Results: Of the total study sample of 782 women, 147 (18.8%)had polycystic ovarian cyst. The highest prevalence (32.7% and 43%) was among the age group 18-27 years and participants with high body mass index (31-≥40).There was a statistically significant correlation between menstrual cycle irregularities and serum prolactin andserum testosterone. The highest polycystic ovary prevalence was found among participants with a history of amenorrhea and oligomenorrhoea, 92.3% and 75.2%, respectively.

Conclusion: We observed that polycystic ovary is an age-related disease and the prevalence of the disease decreases with age. The highest prevalence was seen among the age group of 18-27 years and least in the age group of 38-47 years. No patients with polycystic ovary were found above 48 years.

References

Polycystic Ovary Syndrome (PCOS): Condition Information. (Accessed December 13, 2018 at https://www.nichd.nih.gov/health/topics/pcos).

Abbott DH, Dumesic DA, Franks S. REVIEW Developmental origin of polycystic ovary syndrome – a hypothesis. J Endocrinol 2002; 174:1–5.

Knochenhauer ES, Key TJ, Kahsar-Miller, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black 7 white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998; 83(9):3078–82.

Patel SM, Nestler JF. Fertility in polycystic ovary syndrome. Endocrinol Metab Clin North Am 2006; 35(1):137–55.

Moran LJ, Pasqual R, Teede HJ, Hoeger KM, Norman RJ. Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society. Fertil Steril 2009; 92(6):1966–82.

Balen A. The current understanding of polycystic ovary syndrome. The Obstetrician & Gynaecologist 2004; 6:66–74.

The Rotterdam ESHRE/ASRM-Sponsered PCOS Consensus Workshop Group: The Netherlands. Revised 2003 consensus on diagnostic criteria and long term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81:19–25.

Joyce K. Polycystic ovarian syndrome. Journal of Midwifery & Women's Health 2007; 51:415–22.

Balen A, Homburg R. Franks S. Defining polycystic ovary syndrome. BMJ 2009; 338:a2968.

Swanson M, Sauerbrei EE, Cooperbeg PL. Medical implications of ultrasonically detected polycystic ovaries. J Clin Ultrasound 1981; 9:219.

Atiomo WU, Pearson S, Shaw S, Prentice A, Dubbins P: Ultrasound criteria in the diagnosis of polycystic ovary syndrome(PCOS). Ultrasound Med Biol 2000; 26:977–80.

Tang T, Glanville J, Hayden CJ, White D, Barth JH, Balen AH. Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicenter study Hum Reprod 2006; 21(1):80–9.

Izzo CR. Infertilidade de causa hormonal para o ginecologests. Boletim da SBRH: Artigos Cientificos 2008; 6(2):1–3.

National Heart, Lung, and Blood Institute. Clinical guidelines on the identification, evaluation and treatment of overweight and obesity in adults. NIH publication No.98-4083. Bethesda (MD) Department of Health and Human Services. National Institutes of Health; 1998.

Pache TD, Wladimiroff JW, de Jong FH, Hop WC, Fauser BC. Growth patterns of nondominant ovarian follicles during the normal menstrual cycle. Fertil Steril 1990; 54:638–42.

Sample WF, Lippe BM, Gyepes MT. Gray-scale ultrasonography of the normal female pelvis. Radiology 1977; 125:477–83.

Mujeeb S, Masroor I, Najmi N, Can ultrasound substitute laparoscopy in diagnosis of polycystic ovary syndrome.PJR 2008; 18:5–8.

Botosis D, Kassanos D, Pyrgiolis E, Zourlas PA. Sonographic incidence of polycystic ovaries in gynecological population. Ultrasound Obstet Gynecol 1995; 6(3):182–5.

Williamson K, Gunn AJ, Johnson N, Milsom SR. The impact of ethnicity on the presentation of polycystic ovarian syndrome. Aust NZJ Obstet Gynaecol 2001; 41(2):202–6.

Koivunen R, Laatikainin T, Tomas C, H Uhtaniemi T, Tapanainen J, Martin KH. The prevalence of polycystic ovaries in healthy women. Acta Obstet Gynecol Scand 1999; 78:137–41.

Tabassum K. Ultrasonographic Prevalence of Polycystic Ovarian Syndrome In different Age Groups. Indian J Clin Pract 2014; 25(6):561–4.

Ganbineri A, Pelusi C, Vieeneti V, Pagotto U, Pasquali Obesity and polycystic ovary syndrome. Inf J Obesity Related Disorders 2006; 26:883–96.

Lo JC, Feigenbaum SL, Yang J, Pressman AR, Selby JV, Go AS. Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome. J Clin Endocrinol Metab 2006; 91(4):1357–63.

Tamimi W, Siddiqui IA, Tamim H, AlEisa N, Adham M. Effect of body mass index on clinical manifestations in patients with polycystic ovary syndrome. Int J Gynecol Obstet 2009; 107(1):54–7.

Hussein B, Alalaf S. Prevalence and characteristics of polycystic ovarian syndrome in a sample of infertile Kurdish women attending IVF infertility center in maternity teaching hospital of Erbil city. OJOG 2013; 3(7):577–85.

Rich-Edwards JW, Spiegelman D, Garland M, Hertzmark E, Hunter DJ, Colditz GA, et al. Physical activity, body mass index and ovulatory disorder infertility. Epidemiology 2002; 13(2):184–90.

Cho LW, Jayagopal V, Kilpatric ES, Holding S, Atkin SL. LH/FSH ratio has little use in the diagnosis of polycystic ovarian syndrome. Ann Clin Biochem 2006; 43:217–9.

Legro RS, Chiu P, Kunselman AR, Bentley CM, Dodson WC, Dunaif A. Polycystic ovaries are common in women with Hyperandrogenic chronic anovulation but do not predict metabolic or reproductive phenotype. J Clin Endocrinol Metab 2005; 9(5):2571–9.

Duijkers IJ, Klipping C. Polycystic ovaries, as defined by the 2003 Rotterdam consensus criteria, is found to be very common in healthy women. Gynecol Endocrinol 2010; 26(3):152–60.

Azziz R, Marin C, Hoq L, Badamgarav E, Song P. Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. J Clin Endocrinol Metab 2005; 90:4650–8.

Crosgnani PG, Nicolosi AE. Polycystic ovarian disease: heritability and heterogeneity. Hum Reprod 2001; 7:3–7.

Ramanand SJ, Ghongane BB, Ramanand JB, Patwardhan MH, Ghanghas RR, Jain SS. Clinical characteristics of polycystic ovary syndrome in Indian women. Indian J Endocrinol Metab 2013; 17(1):138–45.

Haq F, Aftab O, Rizvi J. Clinical, biochemical and ultrasonographic features of infertile women with polycystic ovarian syndrome. JCPSP 2007; 17(2):76–80.

Aziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004; 89(6):2745–9.

Hassa H, Tamir HM, Yildiz BO. Comparison of clinical and laboratory characteristic of cases with polycystic ovarian syndrome based on Rotterdam's criteria and women whose clinical sign are oligo/anovulation or hirsutism. Arch Gynecol Obstet 2006; 274:227–32.

Balen AH, Conway GS, Kaltsas G, Techatrasak K, Manning PJ, West C, et al. Polycystic ovary syndrome: the spectrum of the disorder in 1471 patient. Hum Reprod 1995; 10(8):2107–11.

Published
2019-04-23
How to Cite
Jamal, A., Sedeq, M., & Ismael, R. (2019). Ultrasonographic prevalence of polycystic ovarian morphology among women of reproductive age group. Zanco Journal of Medical Sciences (Zanco J Med Sci), 23(1), 57-65. https://doi.org/10.15218/zjms.2019.008
Section
Original Articles