Relationship between type II diabetes mellitus and Helicobacter pylori infection in Erbil city

Rawaz D. Tawfeeq; Zahra A. Amin; Sheila M. Nuraddin; Aveen Jalal; Sayran K. Hama Baiz

doi:10.15218/zjms.2019.006

Authors

Rawaz D. Tawfeeq Department of Clinical Analysis, College of Pharmacy, Hawler Medical University, Erbil, Iraq
Zahra A. Amin Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Iraq
Sheila M. Nuraddin Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Iraq
Aveen Jalal Ministry of Health, Erbil, Iraq
Sayran K. Hama Baiz Department of Clinical Analysis, College of Pharmacy, Hawler Medical University, Erbil, Iraq

DOI:

https://doi.org/10.15218/zjms.2019.006

Keywords:

Type II diabetes mellitus, H. pylori infection, HbA1c

Abstract

Background and objective: Type 2 diabetes mellitus is a metabolic disorder characterized by the increase in blood glucose due to insulin resistance or deficiency of insulin. The subjects are more likely to be prone to infection. So, it could be correlated with Helicobacter pylori infection, which means that gastrointestinal inflammation might be affected by uncontrolled glycemic level. This study aimed to examine the correlation of type II diabetes and infection of gastrointestinal in order to illustrate such complication of diabetes mellitus apart from others.

Methods: A total of 64 persons from Erbil city participated in this cross-sectional study. They were divided into two groups, each group involving 32 persons. The cases group included those suffering from type II diabetes and were selected by simple random sampling method. The other group included those not possessing any types of disease including diabetes mellitus. Examination of Helicobacter pylori, glycated hemoglobin (HbA1c), besides measuring blood pressure and body mass index were performed for all individual subjects in both groups. Chi-Square and unpaired t-test were used for data analysis.

Results: There was a 59% positively Helicobacter pylori in diabetes group whereas there was a 31% positively Helicobacter pylori in non-diabetes mellitus. The difference between the rates of Helicobacter pylori in both groups was statistically significant (P <0.05).

Conclusion: The prevalence of Helicobacter pylori infection in diabetics was significantly higher than the non-diabetics.

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