Evaluation of serum C-reactive protein and lipid profile in patients with myocardial infarction
Keywords:Myocardial infarction, C-reactive protein, Lipid profile
Background and objective: Myocardial infarction is the irreversible death (necrosis) of heart muscle secondary to prolonged lack of oxygen supply (ischemia), when the blood supply to a part of the heart is interrupted, most commonly due to rupture of a vulnerable plaque. The resulting ischemia or oxygen shortage causes damage and potential death of heart tissue. It is a medical emergency, and the leading cause of death worldwide. In this study, we investigated the association of serum C-reactive protein and serum lipid profile with myocardial infarction.
Methods: A cross-sectional study was carried out from January to May 2016 in College of Medicine, Hawler Medical University. The study involved 108 patients with myocardial infarction (70 men and 38 women) in comparison with 50 healthy individuals as the control group (29 men and 21 women).
Results: The levels of serum C-reactive protein were significantly higher (P <0.05) in patients with myocardial infarction in both genders when compared with the control group. There was no statistically significant difference in serum total cholesterol, serum triglyceride and serum LDL-C in patients with myocardial infarction and control group. Regarding serum high-density lipoprotein (HDL-C), there was a statistically significant difference (P <0.01) in patients with myocardial infarction when compared with the control group.
Conclusion: C-reactive protein may play an important role in providing clinicians and biochemists with valuable information regarding diagnosis and following up the patient with suspected myocardial infarction.
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