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Seroprevalence of anti-rubella IgM antibody among pregnant and childbearing women in Diyala province

Abdul-Razak SH. Hasan
College of Medicine, Diyala University, Diyala, Iraq
Abbas A. Al-Duliami
College of Education, Diyala University, Diyala, Iraq
Adnan A. Neima
College of Education, Diyala University, Diyala, Iraq
Asmma H. Al-Jurani
College of Education, Diyala University, Diyala, Iraq
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  • Submited: November 6, 2018
  • Published: November 6, 2018

Abstract

Background and Objective: Rubella infections acquired postnatally are usually mild, but maternal infection during pregnancy is associated with considerable risk of intrauterine fetal infection with multi-system damage.Detection of anti-rubella IgM specific antibodies among pregnant and childbearing women in Baquba city and to explore the effects of   certain demographic factors.

Methods: The present study was conducted in Baquba-Diyala province during the period from April/2007 to September/2008. Ninety pregnant women were chosen from those   attending the primary health care centers in Baquba. They include 30(33.3%) pregnant women who had previous abortions with a mean age 27.2 ± 5.3 years, and 60(66.7%) pregnant women without previous abortion with mean age 23.7± 5.1 years. Additionally, 94 non-pregnant childbearing women were enrolled as a control group. Of those, 37(39.4%) had previous abortions with mean age 33.5 ± 7.8 years, and 57 (60.6%) without abortion, the mean age was 30.7±7.8 years. Certain demographic factors were collected by personal interview. Anti-rubella IgM specific antibody was detected by enzyme-linked immunosorbant assay (ELISA). Data were statistically analyzed using SPSS computer   assisted processing. P value of < 0.05 was considered significant.

Results: The results revealed that 3(5%) of pregnant women without previous abortion and 8(26.7%) of pregnant women who had previous abortions were seropositive for anti-rubella IgM antibody. The difference between the two groups was statistically significant (p= 0.003).Whereas, the IgM seropositivity was insignificantly higher in childbearing women without previous abortion compared to childbearing women who had previous abortions (24.6% vs 16.2%), (p=0.33). Furthermore, the IgM seropositivity among childbearing women without previous abortion was significantly higher compared to pregnant women without previous abortion (24.6% vs 5%), (p=0.003).The presence of life births, time of gestation, and the levels of education significantly affect the seropositivity rate of IgM.

Conclusions: Prenatal screening for anti-rubella IgM antibody is an important tool to identify active infection and to provide obstetric management to avoid the risk of congenital rubella syndrome.

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How to Cite
Hasan, A.-R. S., Al-Duliami, A. A., Neima, A. A., & Al-Jurani, A. H. (2018). Seroprevalence of anti-rubella IgM antibody among pregnant and childbearing women in Diyala province. Zanco Journal of Medical Sciences (Zanco J Med Sci), 14(1 Special), 195–200. Retrieved from https://zjms.hmu.edu.krd/index.php/zjms/article/view/576

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