The Assessment of Specificity & Sensitivity of FNAC in Thyroid Lesions in Erbil

Authors

  • Sirwan Ahmed Garota MB.Ch.B-MS.College of Medicine, Hawler Medical University

DOI:

https://doi.org/10.15218/zjms.2009.018

Keywords:

Thyroid swellings, FNA, Accuracy

Abstract

Background and objective: Fine needle aspiration cytology is regarded as the gold standard investigation in diagnosis of thyroid swellings. The aim of this study was to determine the accuracy of Fine needle aspiration cytology in detection of thyroid swellings in our surgical unit and to assess the correlation between preoperative cytodiagnosis and postoperative histopathological diagnosis.

Methods: Between years 2000-2003, 389 patients underwent thyroid operation by single consultant surgeon for thyroid lesions, 156 patients had preoperative Fine needle aspiration cytology; 6(3.84 %) patients had "unsatisfactory" samples so excluded from the study. the remaining 150 patients were enrolled in this study . Fine needle aspiration results were compared with definitive histological diagnosis following thyroid operation.

Results: Fine needle aspiration cytology done for 156 patients,6 patients had been excluded, analysis revealed 132 (84.6%) non-neoplastic, 14(8.97%) neoplastic and 4 (2.56%) suspicious aspirates,. Of the 150 cases included in the study Histological analysis showed 130(86.66%) benign, 14(9.33%) malignant specimens, 2(1.3%) were false-negative. Fine needle aspiration cytology in this study had a sensitivity, specificity and accuracy rate of 90%, 100%, and 75% respectively for diagnosing thyroid malignancy.

Conclusion: The results are comparable with the current published data and demonstrate that FNA cytology in our hands is accurate investigation for preoperative diagnosis for the detection of thyroid malignancy.

Metrics

Metrics Loading ...

References

Tabaqchali MA, Hanson JM, Johnson SJ, Wadehra V, LennardTW, Proud G. Thyroid aspiration cytology in Newcastle: a six year cytology/histology correlation study. Ann R Coll Surg Engl. 2000; 82(3):149-55.

Ali Rizvi SA, Husain M, Khan S, Mohsin M. A comparative study of fine needle aspiration cytology versus non-aspiration technique in thyroid lesions. Surgeon 2005, 4:273-276.

Nggada HA and Khalil MIA. Fine Needle Aspiration Cytology (FNAC) Technique as a diagnostic tool of tumours in the UMTH, Nigeria. Highland Medical Research Journal. 2003; 1(3): 28-30.

Galera - Davidson H. Diagnostic problems in thyroid fine needle aspirations. Diag Cytopathology 1997, 17:422-428.

Nasuti J, Gupta PK, Baloch ZW. Diagnostic value and cost-effectiveness of on-site evaluation of fine needle aspiration specimens: Review of 5,688 cases. Diagn Cytopathol. 2002;27:1-4.

Cap J, Ryska A, Rehorkova P, Hovorkova E, et al . Sensitivity and specifity of the fine needle aspiration biopsy of the thyroid: clinical point of view. Clinical Endocrinology 1999, 51(4):509-515.

Grant CS, Hay ID, Gough IR, McCarthy PM, Goellner JR. Long term follow-up of patients with benign thyroid FNA cytologic diagnosis. Surgery. 1998; 106: 980-986.

Boyd CA, Eamhardt RC, Dunn JT, Frierson HF, Hanks JB. Pre operative evalution and predictive value of fine needle aspiration and frozen section of thyroid nodules. J Am Coll Surg 1998, 187:494-502.

Caruso D, Mazzaferri EL. Fine needle aspiration biopsy in the management of thyroid nodules. Endocrinologist 1. 1991: 194-202.

Hamburger JI. Diagnosis of thyroid nodules by fine needle biopsy: use and abuse. J Clin Endocrinol Metab 1994; 79:335-339.

Baloch ZW, Sack MJ, Yu GH, Livolsi VA, Gupta PK. Fine needle aspiration of thyroid: an institutional experience. Thyroid 1998, 8:565-569.

Giuffrida D, Gharib H. Controversies in the management of cold, hot, and occult thyroid nodules. Am J Med 1995; 99:642-650.

Gharib H, Goellner JR. Fine-needle aspiration biopsy of the thyroid: an appraisal. Ann Intern Med 1993; 118:282-289.

Suen KC, Abdul-Karim FW, Kaninsky DB, Layfield LJ, Miller TR, Spires SE et al. Guidelines of the Papanicoloau Society of Cytopathology for the examination of Fine-needle aspiration specimens from thyroid nodules. Mod Pathol. 1996; 9:710-715.

Grant CS, Hay ID, Gough IR, McCarthy PM, Goellner JR. Long-term follow-up of patients with benign thyroid fine needle aspiratio cytologic diagnoses. Surgery. 1989; 106: 980-5.

Cap J, Ryska A, Rehorkova P, Hovorkova E, Kerekes Z, Pohnetalova D. Sensitivity and specificity of the fine needle aspiration biopsy of the thyroid: clinical point of view. Clinical endocrinology 1999, 51:509-515.

E. Razmpa, H. Ghanaati, B. Naghibzadeh, P. Mazloom and A. Kashfi ACTA MEDICA IRANICA (The Journal of the Faculty of Medicine, Tehran University of Medical Sciences) 2002; Vol. 40 (No.3).

Downloads

Published

2009-08-02

How to Cite

Garota, S. A. (2009). The Assessment of Specificity & Sensitivity of FNAC in Thyroid Lesions in Erbil. Zanco Journal of Medical Sciences (Zanco J Med Sci), 13(2), 43–49. https://doi.org/10.15218/zjms.2009.018

Issue

Section

Original Articles