Metabolic Syndrome and Serum Leptin Levels in Erbil Population

  • Sanaa G. Hama AL-Mandalawi Department of clinical analysis –College of Pharmacy-Hawler medical university
  • Ava T. Ismail Department of clinical analysis –College of Pharmacy-Hawler medical university
  • Shatha R. Mustaffa Department of clinical analysis –College of Pharmacy-Hawler medical university
Keywords: Leptin, Metabolic syndrome, body mass index

Abstract

Background and Objectives: Metabolic syndrome is a potent risk factor for cardiovascu-lar diseases (CVDs), has not been adequately explored in Erbil individuals and its relation to leptin hormone. The present study aim to evaluate such a relationship between serum leptin and metabolic syndrome in Erbil individuals. Methods: Samples collection were carried out in Razgary teaching hospital, 45 cases with metabolic syndrome and 30 healthy control subjects, anthropometric variables measure-ments (blood pressure, body weight, body height, body mass index) and biochemical tests: fasting, serum glucose, serum triglycerides, high-density lipoprotein cholesterol and serum leptin were obtained from the study samples. Results: Serum leptin levels were significantly higher in females in comparison to the males in metabolic syndromes group (with median 53.6 Vs 23.8 ng/dl with P value < 0.05) with also present statistical significant difference in leptin between metabolic syndrome group and control group in both males and females. No important association between se-rum leptin and each of selected criteria of metabolic syndrome. The observed case-control difference in serum leptin is mainly attributed to gender and body mass index (BMI) differ-ences and not a function of metabolic syndrome itself. Conclusions: Among subjects with metabolic syndrome, only age , gender and body mass index were important in determining the magnitude of serum leptin among cases groups.

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Published
2018-11-01
How to Cite
AL-Mandalawi, S., Ismail, A., & Mustaffa, S. (2018). Metabolic Syndrome and Serum Leptin Levels in Erbil Population. Zanco Journal of Medical Sciences (Zanco J Med Sci), 14(2), 76_84. Retrieved from https://zjms.hmu.edu.krd/index.php/zjms/article/view/537
Section
Original Articles