Metabolic Syndrome and Serum Leptin Levels in Erbil Population

Sanaa G. Hama AL-Mandalawi; Ava T. Ismail; Shatha R. Mustaffa

doi:10.15218/zjms.2010.026

Authors

Sanaa G. Hama AL-Mandalawi Department of clinical analysis –College of Pharmacy-Hawler medical university
Ava T. Ismail Department of clinical analysis –College of Pharmacy-Hawler medical university
Shatha R. Mustaffa Department of clinical analysis –College of Pharmacy-Hawler medical university

DOI:

https://doi.org/10.15218/zjms.2010.026

Keywords:

Leptin, Metabolic syndrome, body mass index

Abstract

Background and objective: Metabolic syndrome is a potent risk factor for cardiovascu-lar diseases (CVDs), has not been adequately explored in Erbil individuals and its relation to leptin hormone. The present study aim to evaluate such a relationship between serum leptin and metabolic syndrome in Erbil individuals.

Methods: Samples collection were carried out in Razgary teaching hospital, 45 cases with metabolic syndrome and 30 healthy control subjects, anthropometric variables measure-ments (blood pressure, body weight, body height, body mass index) and biochemical tests: fasting, serum glucose, serum triglycerides, high-density lipoprotein cholesterol and serum leptin were obtained from the study samples.

Results: Serum leptin levels were significantly higher in females in comparison to the males in metabolic syndromes group (with median 53.6 Vs 23.8 ng/dl with P value < 0.05) with also present statistical significant difference in leptin between metabolic syndrome group and control group in both males and females. No important association between se-rum leptin and each of selected criteria of metabolic syndrome. The observed case-control difference in serum leptin is mainly attributed to gender and body mass index (BMI) differ-ences and not a function of metabolic syndrome itself.

Conclusion: Among subjects with metabolic syndrome, only age , gender and body mass index were important in determining the magnitude of serum leptin among cases groups.

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