Clinical Assessment Of Melasma In Patients Attending The Department Of Dermatology And Venereology At Rizgary Teaching Hospital In Erbil City
AbstractBackground and Objectives: Melasma is an acquired and symmetric hyperpigmentation of the face. The aim of this study was to assess clinical varieties, aggravating factors of melasma, distribution among different age and sex groups and observed diseases. Methods: This descriptive study was conducted on 210 patients with melasma attending the department of Dermatology and Venereology at Rizgary Teaching Hospital in Erbil city. Data were collected from November 2007 to the end of June 2008. All patients and both sexes were included in the study except for patients who received treatment during last two months of pres-entation. A questionnaire was prepared and full history and a thorough examination was done for each patient. Results: The study showed that 83.33% of the patients were females with a mean age of 23.71 years. Main factors found to induce or exacerbate melasma were sunlight (71.9%) and emotional stress (65.7%). The most common morphological type was centrofacial (70.95%). Wood’s light examination showed epidermal type predominance. Conclusions: Melasma is a disease of reproductive period. Sunlight and emotional stress are the most common aggravating factor. The most common morphological type of melasma seen was centrofacial. Epidermal type of pigment predominates in most patients with melasma.
Kang WH, Yoon KH, Lee E-s, Kim J, Lee KB, Yim H et al. Melasma: histopathological characteris-tics in 56 Korean patients. Br J Dermatol. 2002; 1462:228 -237.
Muzaffar F, Hussain I, Haroon TS. Physiologic skin changes during pregnancy: A study of 140 cases Int J Dermatol. 1998; 37:429-431.
Kimbrough-Green CK, Griffiths CE, Finkel LJ, Hamilton TA, Bulengo-Ransby SM, Ellis CN et al . Topical retinoic acid (tretinoin) for melasma in black patients. Arch Dermatol. 1994; 130:727-733.
Lim JT. Treatment of melasma using kojic acid in a gel containing hydroquinone and glycolic acid. Dermatol Surg. 1999; 25:282-284.
Vazquez M, Maldonado H, Benaman C, Sanchez JL. Melasma in man: a clinical and histological study. Int J Dermatol. 1998; 27:25-27.
Sanchez NP, Pathak MA, Sato S, Fitzpatrick TB, Sanchez JL, Minhm MC Jr. Melasma: a clinical, light microscopic, ultrastructural and immunofluo-rescence study. J Am Acad Dermatol. 1981; 4:698-710.
Grimes PE. Melasma. Etiologic and therapeutic considerations. Arch Dermatol. 1995; 131(12):1453-1457.
Pandya AG, Guevara IL. Disorders of Hyperpig-mentation. Dermatol Clin. 2000; 181:91–98.
Sharquie KE, AL-Mashhadani SA, Salman HA. Topical 10% Zinc Sulfate Solution for Treatment of Melasma. Dermatol surg. 2008; 34:1-4.
Garg VK, Sarkar R, Agarwal R . Comparative Evaluation of Beneficiary Effects of Priming Agents (2% Hydroquinone and 0.025% Retinoic Acid) in the Treatment of Melasma with Glycolic Acid Peels. Dermatol surg. 2008; 34:1-9.
Dhahir SA (1999). Melasma in Iraqi women; a clinical and histological study. An F.I.C.M.S. The-sis in Dermatology and Venereology. Baghdad: University of Baghdad, College of Medicine.
. Freitag FM, Cestari TF, Leopoldo LR, Paludo P, Boza JC. Effect of melasma on quality of life in a sample of women living in southern Brazil. J eur acad dermatol ven. 2008; 22:655-662.
Duarte I, Lage ACC. Frequency of dermatoses associated with cosmetics. Contact Derm. 2007; 56 (4):211–213.
Moin A, Jabery Z, Fallah N. Prevalence and awareness of melasma during pregnancy. Int j dermatol. 2005; 45:285-288.
Mohammad KI. Melasma in Iraq; clinical and epidemiological study. 1989 Dissertation in Der-matology and Venereology. Baghdad: University of Baghdad, College of Medicine.
Sarkar R, Jain RK, Puri P. Melasma in Indian males. Dermatol Surg. 2003; 29:204.
Goh CL, Dlova CN. A retrospective study on the clinical presentation and treatment outcome of melasma in a tertiary dermatological referral cen-tre in Singapore. Singapore Med J. 1999; 40:455-458.
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