The Effect of Precordial ST-Segment Depression in Inferior ST-Segment Elevation Myocardial Infarction on Left Ventricular Systolic Function :Two-Dimensional Echocardiographic Study
Keywords:
Left ventricular systolic functionAbstract
Background and Objectives: The importance of precordial ST-segment depression in patients with early inferior ST-segment elevation myocardial infarction remain unclear. Many studies have reported that patients with precordial ST-segment depression appear to have large infarctions.
The objectives of this study was to evaluate the effect of precordial ST-segment depression in patients with early inferior ST-segment elevation myocardial infarction on the left ventricular systolic function and left ventricular regional wall abnormalities.
Patients & Methods: Fifty eight patients with first inferior ST-segments elevation myocardial infarction (37 male, 21 female), their ages ranged from 30-91year,mean age 60.59±11.21 who underwent thrombolysis in the Coronary Care Unit of Erbil Teaching Hospital for the period from August 2008 to August 2009 were included in this study. Two-dimensional echocardiography was performed in the first week of acute inferior myocardial infarction. Patients were classified according to the absence (group I, 30 ,51.72%) or presence (group II ,28 , 48.28%) of precordial ST- segment depression .
Results: Group-II patients had a higher significant incidence of left ventricular systolic dysfunction (8,28.57%) than group I (2,6.67%),P=0.027 ,despite thrombolytic therapy (alteplase). Group-II patients had higher significant incidence of left ventricular regional wall abnormalities ( 12,42.9%) than group-I (3,10%),P 0.00 ,despite thrombolytic therapy (alteplase).
Conclusions: Early two-dimensional echocardiography is recommended for patients with inferior ST-segment elevation myocardial infarction associated with precordial ST-segment depression for the earliest detection of regional wall abnormalities and left ventricular systolic dysfunction.
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