Role of mesoprostol in the management of first trimester incomplete abortion
DOI:
https://doi.org/10.15218/zjms.2012.0023Keywords:
Incomplete abortion, mesoprostol, spontaneous abortionAbstract
Background and objectives: Surgical treatment has been a traditional way of treatment of incomplete abortion. Expectant management and medical treatment can reduce costs and complications generated by surgery. Current study was designed to determine the success rate of treatment of incomplete abortion by mesoprostol thus avoiding surgical intervention. Moreover, factors which can impair efficacy of the treatment were investigated.
Method: The sample size included 100 patients with first trimester incomplete abortion attending Maternity Teaching Hospital in Erbil city/ Kurdistan Region / North of Iraq between October, 1st 2009 and March, 1st 2010 being assigned to receive 400 µg mesoprostol orally. A week later the patients were specifically examined to verify that complete abortion had been occurred. A second dose was administered if complete abortion was not yet achieved, provided that the patient was hemo-dynamically stable and notably no substantial bleeding or infection been noticed.
Results: The success rate of the treatment was 62% and 93% after first and second dose respectively. The difference in response to the treatment was related to the difference in endometrial thickness and gestational age. No any serious complication was reported.
Conclusion: Mesoprostol administered orally is an effective method in treating first trimester incomplete abortion.
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