Association of pre-eclampsia with dyslipideamia

  • Sinan Butrus Garabet Directory of Clinical standards & Guidelines, Kurdistan Board for Medical Specialties, Erbil, Iraq
Keywords: Pre-eclampsia, cholesterol, triglycerides, low density lipoprotein (LDL)

Abstract

Background and objective: Pre-eclampsia and eclampsia are claimed to be associated with disturbances in lipid profile. The purpose of this study was to determine any significant association between pre-eclampsia/eclampsia with lipid profile disturbances.

Methods: This prospective study evaluated lipid profile in the second half of pregnancy in 38 pre-eclamptic, 21 ecalmptic woman and compared to 41 age matched healthy pregnant women served as a control for the period of February 2010 – January 2011. Results: Pre-eclamptic women showed a significant increase in the mean serum cholesterol concentration (243.9 mg/dL) during the second trimester when compared with the healthy pregnant controls (212.9 mg/dL), eclamptic women had even a significant higher cholesterol level at a mean of (288.1 mg/dL). Triglyceride level significantly increased in pre-eclamptic (281.7 mg/dL) and eclamptic women (307.4 mg/dL) compared to healthy pregnant control (207.5 mg/dL). LDL level also showed significant increase in pre-eclamtic {143.7 mg/dL} and eclamptic cases (156.5 mg/dL). HDL level though was decreased in pre-eclamptic {41.5 mg/dL} and eclamptic (40.8 mg/dL) but these changes were not significant.

Conclusion: Pre-eclampsia and eclampsia are associated with dyslipidemia. This association may be significant in understanding the pathologic processes of preeclampsia and may help in developing strategies for prevention or early diagnosis of the disorder.

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Published
2018-10-02
How to Cite
Garabet, S. (2018). Association of pre-eclampsia with dyslipideamia. Zanco Journal of Medical Sciences (Zanco J Med Sci), 17(2), 388-392. https://doi.org/10.15218/zjms.2013.0021
Section
Original Articles