Midline lethal granuloma: Case report and review of literature


  • Ali A. Alzubaidee Kurdistan Board for Medical Specialities, Consultant in Rizgary Teaching Hospital, Erbil, Iraq.
  • Shaheen Ali Ahmed Department of , College of Dentistry, Hawler Medical University, Erbil, Iraq.




Lethal midline granuloma, LymphomaWegener’s granuloamatosis, Polymorphic reticulosis, Idiopathic midline granuloma


Lethal midline granuloma syndrome is a clinical term used generally to describe a rare clinical entity, of unknown aetiology, characterized by progressive destruction of face, nose, para-nasal sinuses, and palate, oral and para-oral structures. Diagnosis is often difficult and requires expert clinical and histopathological examination of the lesion. A case of advanced high–grade lymphoma is reported as it was misdiagnosed and not treated properly for several months. After final diagnosis, a combined radio and chemotherapy were offered to the patient, but unfortunately the patient died because there was no response to treatment.


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How to Cite

Alzubaidee, A. A., & Ahmed, S. A. (2015). Midline lethal granuloma: Case report and review of literature. Zanco Journal of Medical Sciences (Zanco J Med Sci), 19(1), 935_937. https://doi.org/10.15218/zjms.2015.0002



Original Articles