C-reactive protein as a biochemical marker for idiopathic preterm delivery


  • Rose B. Al-Meerany Maternity Teaching Hospital, Erbil, Iraq.
  • Sabat A.M. Barawi Department of obstetrics and gynecology, college of medicine, Hawler Medical University, Erbil, Iraq.




C-reactive protein, premature uterine contractions, premature delivery, pre-term delivery


Background and objective: Estimation of C-reactive protein is a simple method and could be helpful in detecting cases at risk for pre-term delivery. In this study we examined the association of maternal C-reactive protein in second trimester with risk of occurrence of preterm delivery later on.

Methods: A prospective case-cohort study was conducted between June 2011 and July 2012 at Maternity Teaching Hospital Iraq- Erbil. The sample size was 205 women at gestational age of 20+0 weeks to 26+6 weeks and after exclusion of all risk factors for preterm delivery. High-sensitivity C-reactive protein assays were performed on serum samples.  

Results: Median concentration of C-reactive protein was 4.7 mg/liter. No significant association was found between high level of C-reactive protein and occurrence of preterm delivery (P = 0.78).

Conclusion: Measurement of C-reactive protein in second trimester cannot be used as an indicator for pre-term delivery.


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How to Cite

Al-Meerany, R. B., & Barawi, S. A. (2015). C-reactive protein as a biochemical marker for idiopathic preterm delivery. Zanco Journal of Medical Sciences (Zanco J Med Sci), 19(3), 1123–1129. https://doi.org/10.15218/zjms.2015.0042



Original Articles