C-reactive protein as a biochemical marker for idiopathic preterm delivery
Keywords:C-reactive protein, premature uterine contractions, premature delivery, pre-term delivery
Background and objective: Estimation of C-reactive protein is a simple method and could be helpful in detecting cases at risk for pre-term delivery. In this study we examined the association of maternal C-reactive protein in second trimester with risk of occurrence of preterm delivery later on.
Methods: A prospective case-cohort study was conducted between June 2011 and July 2012 at Maternity Teaching Hospital Iraq- Erbil. The sample size was 205 women at gestational age of 20+0 weeks to 26+6 weeks and after exclusion of all risk factors for preterm delivery. High-sensitivity C-reactive protein assays were performed on serum samples.
Results: Median concentration of C-reactive protein was 4.7 mg/liter. No significant association was found between high level of C-reactive protein and occurrence of preterm delivery (P = 0.78).
Conclusion: Measurement of C-reactive protein in second trimester cannot be used as an indicator for pre-term delivery.
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