Prospective comparison of primary wound closure with tissue- adhesive versus suture materials


  • Rasim Yousif Marbin Department of plastic surgery, college of medicine,Hawler medical university, Erbil, Iraq.
  • Jalal Hamasalih Fattah Department of plastic surgery, college of medicine,Hawler medical university, Erbil, Iraq.



Tissue adhesive, cosmetic outcome, complications


Background and Objectives: Nowadays the final outcome of wound closure using tissue adhesives and suture material is making a real competition for better results. Cosmetic outcome is regarded as the first demand for the patients. The aim of this study was to make a comparison between the two closure methods in terms of cosmetic outcome, complication and patients’ satisfaction. Method: A prospective comparative study was conducted at Rizgary Teaching Hospital and West Erbil Emergency Hospital in Erbil city from March 2012 to March 2013. A total of 105 patients were included in the study. The method of closure was selected alternatively between tissue adhesive (octylcyanoacrylate) and suture material. Analysis for cosmetic outcome, complications and patients’ satisfaction were done using the statistical package for the social sciences (version 19). Results: The complications were 25% (13 patients) in the tissue adhesive group and 18% (9 patients) in the sutured group. Of the 44 patients in the tissue adhesive group, 86.4% (38 patients) were satisfied; while of the 61 patients in the sutured group, 88% (54 patients) were satisfied with the end result. Excellent cosmetic outcome achieved in 77.3% in the tissue adhesive group and 80.3% in the sutured group. Conclusion: Tissue adhesive (octylcyanoacrylate) is effective and reliable in primary skin closure, yielding similar cosmetic results to standard suturing method. Tissue adhesive is faster and offers several practical advantages over suture repair.


Metrics Loading ...


Hogler JS, Wandersee SC, Hale DB. Cosmetic outcomes of facial lacerations repaired with tissue-adhesive, absorbable, and non-absorbable sutures. AJEM 2003; 22(4): 254-5.

Elmore J, Smith E, Kirsch A. Sutureless Circumcision Using 2-Octyl Cyanoacrylate (Dermabond):Appraisal After18-Month Experience. Urology J 2007; 70 : 294-9.

Beam JW. Tissue Adhesives for Simple Traumatic Lacerations. J Athl Train. 2008; 43(2): 222–4.

Bruns TB, Worthington JM Using tissue adhesive for wound repair: a practical guide to dermabond, Am Fam Physician 2000; 61(5):1383-8.

Kumar P., Basic principles and techniques of plastic surgery. Hyderabad , Paras medical publisher,1st ed., 2001. 1: 24-6.

Weinzweig J. Plastic surgery secrets. Elsevier: 2010 ,2nd ed.; 29-33.

Brown J, Campbell B, Drongowski R . A prospective, randomized comparison of skin adhesive and subcuticular suture for closure of pediatric hernia incisions: cost and cosmetic considerations. Journal of Pediatric Surgery 2009 ; 44: 1418–22.

Kaminer S, Arndt A, Dover S, Rohrer E, Zachary B. Atlas of cosmetic surgery. Elsevier; 2nd ed.; 2009. 1: 408.

Singer AJ, Kinariwala M, Lirov R, Thode HC. Patterns of use of topical skin adhesives in the emergency department. Acad Emerg Med 2010; 17(6):670-2.

Chung C, Rudkin G. Lacerations. Greer S., Benhaim P., Lorenz H., Chang J., Hedrick H. Handbook of plastic surgery. Marcel Dekker; 2004. 1st ed.; 114-7.

Farion K, Osmond MH, Hartling L, Russell K, Klassen T, Crumley E, et al.Tissue adhesives of traumatic lacerations in children and adults. The Cochrane Library 2002; (3):223-7.

Stephen J. Mathes. Plastic surgery. Saunders-Elsevier. 2006; 2nd ed. 1 ; 222-3.

Noordzij J, Foresman P, Rodeheaver G, Quinn J, Edlich R. Tissue adhesive wound repair revisited. JEM. 2008; 12 (5):645-9

Handschel J G, Depprich R A, Dirksen D, Runte C, Zimmermann A, Kübler N R. A prospective comparison of octyl-2-cyanoacrylate and suture in standardized facial wounds. Oral And Maxillofacial surgery 2001; 137(9):1177-80.

Perry AW. Severe Allergic Reaction to Dermabond, ASJ. 2009 ; 29: 314-6.

Greene D R, Koch JK, Goode RL. Efficacy of octyl-2-cyanoacrylate tissue glue in blepharoplasty. Archives of facial plastic surgery 1999; 1(4):292-6.

Strauss E, Weil W, Jordan C, Paksima N. A Prospective, Randomized, Controlled Trial of 2-Octylcyanoacrylate Versus Suture Repair for Nail Bed Injuries. JHS 2008 ; 33 (2) : 250-3.

Dragu F, Schwartz S, Beier P, Kneser U, Bach D, Horch E. Foreign body reaction after usage of tissue adhesives for skin closure: a case report and review of the literature. Archives of Orthopaedic and Trauma Surgery 2009; 129(2):167-9.

Rimmer J, Singh A, Banwell P, Clarke PM, Evans PR. The Use of Octyl-2-Cyanoacrylate (Dermabond™) Tissue Adhesive for Skin Closure in Head and Neck Surgery. ARSE 2006; 88(4): 412–3.

Jeffrey J. Essentials of plastic surgery. Karen Berger; 2007; 1st ed. 1: 16-19.

Coulthard PE, Esposito M, Worthington HV, van der Elst M, van Waes OJ, DarceyJ. Tissue adhesives for closure of surgical incisions. The Cochrane Library. 2010; 12 (5):345-8.




How to Cite

Marbin, R. Y., & Fattah, J. H. (2015). Prospective comparison of primary wound closure with tissue- adhesive versus suture materials. Zanco Journal of Medical Sciences (Zanco J Med Sci), 19(1), 859_865.



Original Articles