Echocardiographic diastolic dysfunction among hypertensive patients


  • Halgurd F. Ahmed Department of Internal Medicine, Rozh-halat Emergency Hospital, Erbil, Iraq.



Diastolic dysfunction, Left ventricular hypertrophy, Echocardiography, Hypertension


Background and objective: Hypertension is a very common medical disorder, affecting nearly 40% of our population. Diastolic dysfunction is one of complications that happens and is regarded as a predictive of subsequent heart failure. The aim of this study was to determine the frequency of left ventricular diastolic dysfunction by echocardiography among hypertensive patients. Methods: This study involved 150 hypertensive cases (82 female and 68 male) age from 25-81 years old. Transthoracic echocardiography approach, using SIEMENS SONOLINE Omnia 2005 machine with the probe of p4-2 was used by the researcher. A comparative 150 normal non-hypertensive healthy adults with hypertensive patients are examined again by echocardiography. The parameter for the diastolic dysfunction measurement is E/A ratio. Results: It was found that 88 (58.7%) of hypertensive patients have diastolic dysfunction, while 4.9% of non-hypertensive group have diastolic dysfunction with significant statistical differences between both groups (P <0.001), who were age >60years have 79%, while age 25-35years old have 21% (P <0.001). Among left ventricular hypertrophy patients, 87.5%, versus 12.5% have diastolic dysfunction (P <0.001). Females are more liable for diastolic dysfunction, who have 70.7% than males who have 44.1% (P <0.001). Conclusion: Diastolic dysfunction is common among hypertensive patients, particularly among females, aged, and who have echocardiographic criteria of left ventricular hypertrophy, represent risk factors for diastolic dysfunction.


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Thais C, Barry A, Patricia A, Stephen T, Iftikhar J. Sex Differences in Arterial Stiffness and Ventricular-Arterial Interactions. J Am Coll Cardiol 2013; 61(1):96-103.

Aaron M, Christopher G,Horng H. The Development of Heart Failure in Patients with Diabetes Mellitus and Pre-Clinical Diastolic Dysfunction : A Population-Based Study. J Am Coll Cardiol 2010; 55(4):300-5.

Paul M, John A, Lisa C, Sherry L, Lynn K, Kent R,et al. Impaired Natriuretic and Renal Endocrine Response to Acute Volume Expansion in Pre-Clinical Systolic and Diastolic Dysfunction. J Am CollCardiol 2011;58(20):2095-103.

Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM. Trends in prevalence and outcome of heart failure with preserved ejection fraction, N Engl J Med 2006; 355 :251-9

Frank E,Götz G, Hans-Dirk D, Stefan F, Rolf W, Raoul S,et al. Exercise Training Improves Exercise Capacity and Diastolic Function in Patients with Heart Failure with Preserved Ejection Fraction: Results of the Ex-DHF (Exercise training in Diastolic Heart Failure) Pilot Study.J Am Coll Cardiol 2011; 58(17):1780-91.

Rowlens M,Rakesh M, James B, Kent R, Naser M, Jae K, et al. Diastolic Dysfunction in Patients Undergoing Cardiac Surgery: A Pathophysiological Mechanism Underlying the Initiation of New-Onset Post-Operative Atrial Fibrillation. J Am CollCardiol 2011; 58(9):953-61.

Abdul Rashid K, Muhammad Q. Association and pattern of diastolic dysfunction in patients of metabolic syndrome.J Ayub Med Coll Abbottabad 2008; 20(2):70-5

Patil M, Burji N, Echocardiographic evaluation of diastolic dysfunction in hypertensive patients. J Assoc Physicians India 2012; 60:23-6.

The Eighth Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure.US Department of Health and Human Services./guidelines/hypertension/jnc8.Accessed January 6, 2014.

Meijs M, Bots M,Vonken E, Cramer M, Melman P,Velthuis B, et al. A prediction model for left ventricular hypertrophy in hypertension.Neth Heart J 2007;15(9): 295–8.

TromsS.Mitral flow derived Doppler indices of left ventricular diastolic function. Eur.heart J 2000; 21: 1376-86

Levy D, Larson M,Vasan R, Kannel W. The progression from hypertension to congestive heart failure. JAMA 1996; 275:1557-62.

Donald M, LarsonM,Leip E. Lifetime risk for developing congestive heart failure. Circulation.2002; 106:3068-9.

Masoudi F,Havranek E, Smith G. Gender, age, and heart failure with preserved left ventricular systolic function. J Am Coll Cardiol 2003; 41:217-22.

Drazner MH, Rame JE, Marino EK, Gottdiener JS, Kitzman DW, Gardin JM, et al. Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study. J Am CollCardiol 2004; 43:2207-15.

Koren M, Devereux R, Casale P. Role of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 1991; 114:345-8.

Che Q, Martin J, Mohammed A. Beta-blockers for hypertension: Are they going out of style? Cleve Clin J Med 2009; 76(9):533-42.

- Warner J, Metzger C, Kitzman D. Losartan improve exercise tolerance in patients with diastolic dysfunction and hypertensive response to exercise. J Am Coll Cardiol 1999; 33:1567-71.

William W, Parmley M. Efficacy and Safety of Calcium Channel Blockers in Hypertensive Patients with Concomitant Left Ventricular Dysfunction. Clin. Cardiol 1992; 15:235-42.

Mottram P, Haluska B, Leano R. Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure. Circulation 2004; 110:558-63.




How to Cite

Ahmed, H. F. (2015). Echocardiographic diastolic dysfunction among hypertensive patients. Zanco Journal of Medical Sciences (Zanco J Med Sci), 19(1), 853_858.



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