Prophylactic versus postoperative antibiotics in septoplasty


  • Said Mustafa Jaf Department of Surgery, College of Medicine, Hawler Medical University, Erbil, Iraq.
  • Sherzad k. Awla Erbil Directorate of Health, Erbil, Iraq.



Septoplasty, Infection, Prophylactic antibiotics


Background and objective: Septoplasty is one of the most common procedures worldwide in otolaryngology clinics. The use of antibiotics in Septoplasty is a common practice among most otolaryngologists. However, there are few studies proving the efficacy, which is considered unnecessary by some others. This study aimed to compare the efficacy of prophylactic versus postoperative antibiotic in septoplasty and strengthen the evidence base for antibiotic use. 

Methods: This prospective study was conducted on 90 patients that underwent septoplasty over six months period from August 1st, 2012 to January 31st, 2013 in Rizgary Teaching Hospital, Erbil city. They were equally divided into two groups; 45 patients in Group A and 45 patients in Group B. Their age ranged between 17-49 years old. 

Results: No significant difference was observed in reduction of infection rate between Group A and Group B. No any statistically significant difference was found concerning pain, fever, purulent discharge and bleeding. Two of the patients (one from each group) developed septal hematoma.

Conclusions: Infection after septoplasty is rare and if occur is usually minor in nature. The outcome of postoperative antibiotic use does not outweigh that of a single prophylactic dose of antibiotic.


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Alexander D, George F, Joanna M, Johannes Z, Heinrich I, George A. Septoplasty outcome in patients with and without allergic rhinitis. Rhinology 2009; 47:444-9.

Evren E, Mustafa B, Ozan K. Postoperative cephazolin usage is sufficient for preventing infection after septoplasty procedure. Allergy Rhinol 2011; 2.

Irfan K, Ahmet K, Turgut K, Sinasi Y, Erol K. Bacteriemia in septoplasty and septorhinoplasty surgery. Rhinology 2003; 41:76-9.

Rechtweg J, Paolini R, Belmont M, Wax M. Postoperative antibiotic use of septoplasty: a survey of practice habits of the membership of the American Rhinologic Society. Am J Rhinol 2001; 15(5):315-20.

Günaydın R, Aygenc E, Karakullukcu S, Fidan F, Celikkanat S. Nasal packing and transseptal suturing techniques: surgical and anaesthetic perspectives. Eur Arch Otorhinolaryngol 2011; 268:151-6.

Andrews P, East C, Jayaraj S, Badia L, Panagamuwa C, Harding L. Prophylactic vs Postoperative Antibiotic Use in Complex Septorhinoplasty Surgery. Arch Facial Plast Surg 2006; 8:84-7.

Ulrich G, Jan-Olaf G. The Nose As Bacterial Reservoir: Important Differences Between the Vestibule and Cavity. Laryngoscope, Philadelphia: Lippincott Williams & Wilkins, Inc; 2000.

Jonathan P, Arlen D. Prophylactic Antibiotic Use in Head and Neck Surgery. 2012. (accessed on June at

Marcello, Gustavo H, Elder Y, Richard L, Ossamu B. Antibiotics in septoplasty: is it necessary? Brazilian Journal Of Otorhinolaryngology 2005; 71:734-8.

Teichgraeber J, Russo C. Treatment of nasal surgery complications. Ann Plast Surg 1993; 30:80-8.

Danyal A, Pachen E. Surgical Infections and Choice of Antibiotics. In: Townsend. Townsend: Sabiston Textbook of Suregry. 18th edition. New York: Saunders; 2007. PP. 264-79.

Stoelting K, Hillier C. Handbook of Pharmacology and Physiology in Anesthetic Practice. 2nd ed. New York: Lippincott Williams & Wilkins; 2006. PP. 540-56.

Celil G, Engin D, Aydın A. antimicrobial prophylaxis in nasoseptal surgery. KBB-Forum 2007; 6:10-4.




How to Cite

Jaf, S. M., & Awla, S. k. (2016). Prophylactic versus postoperative antibiotics in septoplasty. Zanco Journal of Medical Sciences (Zanco J Med Sci), 20(2), 1323–1329.



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